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Crypto VC firms USA: 36 active since 2025, Pantera joined 14

By NAUT Research · · 6 min read

36 Crypto VC firms USA US venture firms with a crypto round on NAUT, 1 January 2025 to 13 November 2026. Logos: Pantera Capital, Polychain Capital, Paradigm, Blockchain Capital, CMT Digital, Variant, Framework Ventures, General Catalyst, 6th Man Ventures, Dispersion Capital, Ribbit Capital, BITKRAFT Ventures, Breed VC.

Crypto VC firms USA list: NAUT tracks 36 US venture firms that joined at least 1 crypto funding round dated between 1 January 2025 and 13 November 2026, out of 98 US investor rows typed Venture on NAUT. Pantera Capital joined the most (14 rounds), and Blockchain Capital led the most (6 of its 8).

How this list was built: on 13 November 2026, NAUT's data showed 505 live US investor rows, 98 of them typed Venture. 43 of those 98 have a round dated 1 January 2025 or later (the announce date, or the close date where no announce date is stored; the plan for this piece said 42, and the live count is 43). 7 were then dropped, each for its own reason:

  • 2 are trading firms: Jane Street is a market maker, and Jump Trading is a trading firm. Jump Capital, a separate row that NAUT describes as a Chicago venture firm, stays on the list.
  • What If Ventures: its description names mental health and defense, with no crypto focus.
  • BOND and Abstract Ventures: the stored description on each row is about a different company (a handwritten-card startup, and the Abstract consumer chain, which its own text says is not a fund).
  • Figment Capital: its stored description and domain are for Figment's staking business, so the row cannot be shown as the fund.
  • Nima Capital: its description says it is a single-family office, and family offices sit outside a venture list.

Angels and corporates are out because they carry other fund types on NAUT. "Rounds" counts every round on NAUT's record a firm joined in the window; "Led" counts the ones where NAUT marks it lead. "Mean round size" (the avg column) is the average size of the whole rounds a firm joined in the window: it is NAUT's own cut, and it is the round, never the firm's own check, because NAUT does not store each backer's share. 8 of the 36 had their US base or crypto investing confirmed on an outside page (listed under Sources); the rest rely on NAUT's record.

Crypto VC firms USA: which invest only in crypto?

18 of the 36 describe themselves on NAUT as crypto, blockchain or Web3 investors. Together they hold 98 round places in the window, ranked below by rounds joined, then by rounds led.

Firm Rounds (led), avg Sectors, last
14 (1), $20.5M Infrastructure, DeFi, AI; last 15 Oct 2026
11 (2), $33.4M DeFi, L1/2/3, Privacy; last 15 Oct 2026
11 (1), $165.3M DeFi, Prediction Market, DEX; last 14 Jan 2026
8 (3), $11.6M Payment, Neobank, CEX; last 4 Nov 2026
8 (6), $19.7M Infrastructure, RWA, AI; last 5 Nov 2026
8 (2), $46.1M DeFi, AI, Gaming; last 27 Oct 2026
7 (2), $37.1M DeFi, Wallet, Infrastructure; last 4 Nov 2026
7 (0), $22.8M AI, DeFi, DePIN; last 8 Oct 2026
5 (1), $6.6M GambleFi, Gaming, AI; last 2 Nov 2026
4 (1), $12.7M AI, DeFAI, Infrastructure; last 21 Oct 2026
4 (0), $18.6M Infrastructure, L1/2/3, Neobank; last 15 Oct 2026
3 (0), $6.8M AI, CEX, DePIN; last 4 Oct 2026
2 (0), $5.5M DEX, L1/2/3; last 19 Sep 2025
2 (1), $86.3M AI, Insurance, RWA; last 8 Oct 2026
1 (0), $5M DeFi; last 17 Apr 2025
1 (0), $4.5M Stablecoins; last 29 Aug 2025
1 (0), $1.7M DeFi; last 7 Apr 2025
1 (0), $475K No sector tag on record; last 1 Oct 2026

Framework Ventures is "a venture capital company that backs crypto platforms," per Cointelegraph, and Fortune calls Archetype "the New York-based firm" in its third-fund report. Polychain is "an American investment firm based in San Francisco, California," per its Wikipedia entry.

Crypto VC firms USA: which generalists back crypto rounds?

The other 18 invest across sectors and show up in crypto deals: 45 round places between them. Sequoia Capital is the busiest, with 10 rounds and 4 leads, and its mean round of $331.5M is the largest on the list.

Firm Rounds (led), avg Sectors, last
10 (4), $331.5M DeFi, Prediction Market, AI; last 29 Oct 2026
5 (0), $73.7M AI, DeFi, DePIN; last 27 Oct 2026
4 (2), $138.3M AI, DeFi, L1/2/3; last 6 Oct 2026
4 (0), $20.6M Gaming, AI, Infrastructure; last 1 Aug 2025
3 (1), $8M DeFi, Infrastructure; last 6 Oct 2026
2 (0), left out (see note) AI, L1/2/3; last 18 Oct 2025
2 (0), $37M DeFi, DEX, Infrastructure; last 24 Sep 2026
2 (1), $9.3M Neobank, Payment; last 28 Sep 2026
2 (0), $55M AI, DePIN, Infrastructure; last 7 Oct 2026
2 (0), $82.5M AI, L1/2/3, Privacy; last 1 Aug 2025
2 (0), $65M AI, DePIN, Infrastructure; last 7 Oct 2026
1 (0), $2.5M No sector tag on record; last 14 Jun 2025
1 (0), $60M AI; last 7 Oct 2026
1 (0), no amount on record AI, Infrastructure; last 5 Oct 2026
1 (0), $33M AI, SocialFi; last 2 Sep 2025
1 (0), $5M Infrastructure, Privacy; last 19 Aug 2025
1 (0), $40M AI; last 17 Jan 2025
1 (0), $25M No sector tag on record; last 3 Sep 2026

SV Angel's mean round is left out: NAUT holds 2 rounds for it in the window, and the figure looks driven by 1 large round that was not checked. Sapphire Ventures has no amount stored for its round. Fortune describes Ribbit Capital as "the Palo Alto-based Ribbit Capital," and Wikipedia calls Sequoia "an American venture capital firm."

Which US crypto venture funds led the most rounds since 2025?

Rounds led since 1 January 2025, US venture firms with 2 or more
  1. Blockchain Capital6
  2. Sequoia Capital4
  3. North Island Ventures3
  4. Polychain Capital2
  5. CMT Digital2
  6. Variant2
  7. Ribbit Capital2

7 of the 36 US crypto venture capital firms led 2 or more rounds on NAUT's record, and 22 led none; by rounds joined, 15 firms joined 4 or more and 11 joined just 1. AI sits in the top 3 portfolio sectors of 20 firms, DeFi of 13 and Infrastructure of 12.

What this tells a founder raising from US crypto VCs

How a founder can work this list
  1. Filter by sectorKeep the firms whose top sectors match yours, such as 6th Man Ventures for Gaming.
  2. Find a leadStart with the 14 firms that led a round, from Blockchain Capital with 6.
  3. Check recencyFavour the 21 firms with a round in October or November 2026.
  4. Reach the partnerOpen the firm's NAUT page for its team and their channels.

What this tells a BD team selling to crypto investors in the US

  • The 18 crypto-focused firms are the core buyers of crypto services: Pantera Capital, Polychain Capital and Paradigm each joined 11 or more rounds.
  • Each round a firm joins is a portfolio company that may need your product. A firm's NAUT page lists its rounds, so you can work its newest companies first.
  • Generalists such as General Catalyst (5 rounds) and Menlo Ventures (2) are a second ring: fewer crypto deals, larger rounds.

How do you reach the partners at these firms?

Each firm name above links to its NAUT page, which lists the people NAUT holds at that firm and the channels on file for each. Public profiles are free to browse; verified Telegram, email and LinkedIn unlock on a paid plan. Anyone listed can ask NAUT to remove their page at https://naut.so/legal/data-deletion.

Related reading on NAUT: Crypto VC list: 40 investors led 51 rounds in 2026, 31 led once and Crypto VC partners: 141 at 45 funds, 41 with a channel.

Can you pull this data through the NAUT API?

Yes: GET https://api.naut.so/v1/investors/pantera-capital with the header Authorization: Bearer $NAUT_KEY returns Pantera Capital with its team and portfolio, each row carrying the round type, amount, announce date and lead flag, so you can rebuild each firm's round count, lead count, mean round size and last-round date for 5 credits a call. The API docs list every call, and plans start at $49 a month for 3,000 credits. Verified Telegram, email and LinkedIn for the people at these firms unlock on any paid NAUT plan: start a 7-day trial.

Crypto VC firms USA FAQ

Which US venture firms invest in crypto?

NAUT tracks 36 US venture firms with at least 1 crypto round dated 1 January 2025 to 13 November 2026, led by Pantera Capital (14 rounds), Polychain Capital and Paradigm (11 each) and Sequoia Capital (10). 18 of the 36 are crypto-focused and 18 are generalists.

Which US crypto VC led the most rounds since 2025?

Blockchain Capital led 6 of the 8 rounds it joined between 1 January 2025 and 13 November 2026 on NAUT's record, ahead of Sequoia Capital with 4 and North Island Ventures with 3.

How big are the rounds US crypto VCs join?

On NAUT's record from 1 January 2025 to 13 November 2026, the mean round size runs from $475K for DBA to $331.5M for Sequoia Capital, with Pantera Capital at $20.5M. These are whole round sizes, never the firm's own check.

Where can I find the partners at US crypto VC firms and their contact channels?

Each of the 36 US venture firms on this list has a NAUT page with its team and the channels on file, and GET https://api.naut.so/v1/investors/<fund-slug> returns the same firm with its team and portfolio. Verified Telegram, email and LinkedIn unlock on any paid NAUT plan: start a 7-day trial.

Sources

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