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Big Brain Holdings portfolio: 74 companies, 44 with a token

By NAUT Research · · 12 min read

74 Big Brain Holdings portfolio companies tracked on NAUT across 82 rounds, Nov 2021 to Oct 2026. Logos: Avalanche, Monad, Ten, Nillion, MegaETH, Shardeum, Hemi, Blocklords, zkLink, Solayer, Mitosis, Grass.

NAUT tracks 74 companies in the Big Brain Holdings portfolio, across 82 funding rounds announced between November 2021 and October 2026. The 80 rounds with a disclosed size add up to $983.0M, the average round is $12.3M, and 44 of the 74 companies have a live token on NAUT's record.

Data note. Counted on 2 November 2026 from NAUT's own database: the company rows tied to the round records where NAUT names Big Brain Holdings as a backer. NAUT holds the fund under 1 live row, big-brain-holdings, so no rounds are counted twice here. A second row, SOL Big Brain, carries a similar name and 0 round records, and it is a separate entity rather than a duplicate of this fund. 2 of the 82 rounds disclose no amount and 14 carry no announcement date, so the 68 dated rounds set the window above, and a date appears only where NAUT holds one. Each company sits in exactly 1 sector group, the first sector tag NAUT holds for it, so the groups add up to 74; NAUT's tags overlap, so 19 of the 74 companies carry an Infrastructure tag somewhere and 17 a DeFi tag. Group totals are each rounded to $0.1M, so the 8 of them add to $983.1M against the exact $983.04M. The Layer 2 rollup at tenprotocol is named on this page by the X handle NAUT holds for it. Written by NAUT Research.

Every number on this page is recomputed from the live round rows: 82 rounds, $983.0M disclosed and a $12.3M average. None of it is copied from the fund row's stored summary fields, which the 2 November snapshot held at 80 investments, $973.44M deployed and a $12.48M average round, all written before the current round records landed. 23 of the 82 rounds were also checked against a source outside NAUT on 2 November 2026, and the results, including 1 round a source contradicts, sit in their own table below. The other 59 rounds rest on the aggregator records NAUT ingested and were not checked one by one here. NAUT's record flags no firm as lead on 81 of these 82 rounds, so this page makes no claim about who led them.

What is in the Big Brain Holdings portfolio on NAUT?

Sector Companies Rounds Total Token
Infrastructure 11 16 $104.7M 9
AI 9 10 $64.0M 8
DeFi 8 9 $43.1M 6
Gaming 8 8 $76.9M 5
L1/2/3 7 7 $549.0M 7
DEX 5 5 $28.4M 1
Other sectors 10 10 $46.5M 4
No sector tag 16 17 $70.5M 4

Infrastructure, AI and DeFi hold 28 of the 74 companies between them, and base layers hold the money: 7 companies carry $549.0M of the $983.0M disclosed, because Avalanche and Monad alone account for $475.0M. These Big Brain Holdings investments span 5 years, so the sector mix reads as the fund's history rather than its position today.

Big Brain Holdings portfolio companies by sector

Every company below links to its NAUT page, which lists its team, its rounds and the other funds on its cap table. The disclosed column adds every round NAUT records for that company with this fund in it, so a company backed twice shows the sum of both.

Infrastructure (11 companies)

The largest group by company count, and the one that holds both of the fund's 3-round names.

Company Disclosed Latest Token
$25.5M Funding Round, Mar 2024 Yes
$18.2M Seed Round, Oct 2022 Yes
$13.8M Strategic Round, May 2023 Yes
$12.0M No date stored Yes
$7.5M Seed Round, Feb 2024 Yes
$7.0M Pre-Seed Round, Jun 2024 Yes
$7.0M Seed Round, May 2024 Yes
$7.0M No date stored No
$3.0M Seed Round, Sep 2022 Yes
$2.3M No date stored No
$1.5M Seed Round, May 2022 Yes

AI (9 companies)

Company Disclosed Latest Token
$20.0M Funding Round, Dec 2022 Yes
$10.0M Funding Round, Oct 2024 Yes
$9.0M Pre-Series A, Jul 2023 Yes
$8.5M No date stored Yes
$4.5M Seed Round, Dec 2023 Yes
$4.0M Seed Round, Jul 2023 Yes
$3.2M Seed Round, Dec 2023 Yes
$2.5M Seed Round, Jun 2023 Yes
$2.3M No date stored No

DeFi (8 companies)

Company Disclosed Latest Token
$8.0M Seed Round, Apr 2024 Yes
$8.0M No date stored Yes
$7.5M Strategic Round, May 2022 Yes
$6.0M Funding Round, Dec 2024 Yes
$5.0M No date stored No
$3.7M Seed Round, Apr 2022 No
$3.0M Seed Round, Mar 2023 Yes
$1.9M Funding Round, Dec 2023 Yes

Gaming (8 companies)

Company Disclosed Latest Token
$26.2M Series A, Mar 2024 No
$15.0M Seed Round, May 2022 Yes
$12.0M Series A, Jun 2024 No
$6.5M Seed Token Round, Jun 2022 No
$5.5M Funding Round, Jun 2024 Yes
$4.7M Funding Round, Jun 2022 Yes
$3.8M Funding Round, Mar 2022 Yes
$3.2M Seed Round, Oct 2022 Yes

The ZKasino row is the 1 round of the 23 checked here that a source contradicts, and the table below the chart says how it is treated here.

L1/2/3 (7 companies)

Company Disclosed Latest Token
$250.0M OTC Sale, Dec 2024 Yes
$225.0M Funding Round, Apr 2024 Yes
$20.0M Private Round, Jul 2022 Yes
$20.0M No date stored Yes
$15.0M Seed Round, Sep 2024 Yes
$12.0M Seed Round, Aug 2024 Yes
$7.0M Seed Round, May 2024 Yes

DEX (Decentralized Exchange) (5 companies)

Company Disclosed Latest Token
$8.5M Seed Round, Apr 2022 No
$6.0M Funding Round, Apr 2024 Yes
$5.4M Private Round, Jun 2022 No
$5.0M Seed, Oct 2026 No
$3.5M Funding Round, Nov 2022 No

Other sectors (10 companies)

The 9 tags that hold 1 or 2 companies each: stablecoins, RWA, DePIN, wallets, payments, SocialFi, media, money markets and compliance.

Company Disclosed Latest Token
$13.4M No date stored Yes
$6.9M Seed Round, Sep 2025 Yes
$5.0M Funding Round, Apr 2024 Yes
$4.6M Seed, Oct 2026 No
$4.6M Strategic Round, Apr 2024 Yes
$4.0M Funding Round, Aug 2024 No
$2.3M Pre-Seed Round, Nov 2022 No
$2.1M Funding Round, Jul 2023 No
$1.8M Seed Round, May 2022 No
$1.8M Seed Round, Apr 2022 No

No sector tag (16 companies)

These 16 companies carry no sector tag on NAUT, so a sector filter never returns them. They are 16 of the 74, and $70.5M of the disclosed total.

Company Disclosed Latest Token
$12.0M Private Round, Jan 2023 No
$9.0M Series A, Apr 2022 No
$7.5M Seed Round, Jun 2022 No
$7.0M Seed Round, May 2024 Yes
$6.0M Seed Round, Jun 2022 No
$5.5M Strategic Round, Apr 2024 Yes
$4.5M Seed Round, Dec 2023 No
$4.0M Seed and Private Rounds, Jan 2024 Yes
$3.5M Strategic Round, Nov 2021 Yes
$3.0M Private Round, Dec 2021 No
$2.5M Seed Round, Dec 2022 No
$2.1M Strategic Round, Apr 2022 No
$1.8M Angel Round, Apr 2022 No
$1.1M Seed Round, May 2022 No
$1.0M Funding Round, Feb 2024 No
No amount stored No date stored No

How big is a round in the Big Brain Holdings portfolio?

The 80 rounds with a disclosed size run from $1.0M to $250.0M, and the average is $12.3M. That average sits well above the typical round in the set, because the $250.0M and $225.0M rounds pull it up: 43 of the 80 are under $6M.

Round size band Rounds Companies Example
Under $3M 18 17 , $1.5M seed
$3M to under $6M 25 25 , $4.6M seed
$6M to under $10M 21 19 , $6.0M round
$10M to under $20M 10 10 , $15.0M seed
$20M and up 6 6 , $250.0M OTC sale

The bands count rounds, so the 21 rounds in the $6M to $10M band sit at 19 companies, because all 3 of tenprotocol's rounds land there, and the 18 rounds under $3M sit at 17 companies, because 2 of Kima's 3 rounds do. 2 rounds carry no amount and sit in no band, both of them at companies in the tables above, Vest Exchange and Derivio.

Single rounds above $13M, the 9 largest in the set
  1. Avalanche$250.0M
  2. Monad$225.0M
  3. Nillion$20.0M
  4. Oasys$20.0M
  5. MegaETH$20.0M
  6. Shardeum$18.2M
  7. Hemi$15.0M
  8. Blocklords$15.0M
  9. USD.AI (by Permian Labs)$13.4M

Each bar is 1 round rather than a company total, so the companies with 2 or 3 smaller rounds sit outside it, and so does the $26.2M ZKasino round, which would rank 3rd and which the source check below contradicts. The next rounds down are 4 at $12.0M each, at Solayer, Mirror World, Intella X and Sonic.

What the source check found

23 of the 82 rounds were checked against a source outside NAUT on 2 November 2026, starting with the 12 largest and the most recent rounds. 21 came back confirmed, 1 came back contradicted and 1 was not found on the page fetched. 18 of the 21 confirmed rounds carry their source link in Sources below; the 5 rounds that need a word of explanation are here.

Company Round The check Treatment
$26.2M Series A, Mar 2024 the source checked contradicts the fund's place in the round Left out of the chart, the row stays in the tables
$20.0M Private Round, Jul 2022 the page fetched does not name the fund among that round's backers Counted, flagged here
$15.0M Seed Round, Sep 2024 confirmed, the quote was not located on the page fetched Counted, no source link below
$13.4M Series A Round confirmed, the page returned covered another company's round Counted, no source link below
$4.0M Funding Round, Aug 2024 confirmed, the quote was not located on the page fetched Counted, no source link below

Every row above keeps its place in the tables, because hiding a row is how a wrong number survives a rewrite. The 5 rows hold $78.6M of the $983.0M, so read the total as NAUT's record of the fund rather than a figure the fund has published.

Which companies did Big Brain Holdings back more than once?

6 of the 74 companies appear in more than 1 round on NAUT's record, and 68 appear in 1. Kima and tenprotocol carry 3 each, the most in the set.

Company Rounds Disclosed Round types
3 $7.0M Pre-Seed Round, Funding Round, Seed Round
3 $25.5M Funding Round, Funding Round, Private Round
2 $13.8M Strategic Round, Private Funding Round
2 $5.0M Private Round, Seed Round
2 $4.5M Seed Round, Pre-Seed Round
2 $4.5M Seed Round, Pre-Seed Round

Grass and Wynd Network are 2 separate rows on NAUT, 1 described as a network sharing application and the other as a decentralized web proxy network, and each is counted once here.

Who invests alongside Big Brain Holdings?

NAUT records 245 other firms as backers somewhere in these 82 rounds, and 78 of the 82 rounds carry at least 1 of them. An empty backer list on the other 4 rounds means NAUT holds no co-investor for them, rather than that nobody else joined. 16 firms share 6 or more of these rounds, ranked below by rounds shared, with the portfolio companies they share beside it.

Firm Rounds shared Companies
8 8
8 8
8 8
8 8
7 7
7 7
7 7
6 6
6 6
6 6
6 6
6 6
6 6
6 5
6 6
6 6

101 of the 245 firms share 2 or more rounds, so the co-investor list is a second rolodex: an introduction through one of them reaches the same cap table.

What the Big Brain Holdings portfolio tells a BD team

  • Most of these teams raised a small round. 43 of the 80 disclosed rounds are under $6M, so a pitch sized to the $12.3M average aims above most of this list.
  • The 2026 rounds are the warm end. Walapay at $4.6M and PERPTools at $5.0M are the only 2 rounds NAUT dates to 2026, and Bio Protocol at $6.9M is the only 1 from 2025.
  • 44 of the 74 companies have a live token. A team with a token has listings, market makers and a treasury to spend, which is a different sale from a pre-token seed team.
  • 16 companies carry no sector tag. A sector filter never returns them, so work from this list rather than a tag search.

Any crypto VC portfolio list ages from the day it is published, so this page carries the date it was counted and links the NAUT row behind every number.

How a BD team can work this list
  1. Start with the 2026 roundsWalapay at $4.6M and PERPTools at $5.0M are the only 2 rounds NAUT dates to 2026.
  2. Size the pitch to $6M43 of the 80 disclosed rounds are under $6M, so most of these teams raised small.
  3. Work the repeat names6 companies took 2 or more rounds with this fund, led by Kima and tenprotocol at 3 each.
  4. Go through a co-investor16 firms share 6 or more of these 82 rounds, so a warm path through one of them reaches the same table.
  5. Find the person on the NAUT pageEvery company above links to its NAUT page, which lists its team and the channels NAUT holds for them.

What this tells a founder raising

  • NAUT's record names a lead on 1 of these 82 rounds. The other 81 carry no lead flag at all, which is a gap in the record rather than a fact about who led, so find the lead on the round's own NAUT page before you assume one.
  • Match the stage, not the logo. The $20M and up band holds 6 of the 80 rounds. The common path onto this list is a round between $3M and $10M, where 46 of the 80 sit.
  • Your sector has a precedent here. Infrastructure (11 companies), AI (9), DeFi (8) and gaming (8) each carry a worked example you can name in a first message, with the round size NAUT records next to it.

Related reading on NAUT: Shima Capital portfolio: 112 companies, median round $4.0M and Crypto co-investors: 3 steps, 168 on 66 rounds for 1 fund.

Can you pull this data through the NAUT API?

Yes. GET https://api.naut.so/v1/investors/big-brain-holdings with an Authorization: Bearer $NAUT_KEY header returns this fund with its team and its portfolio, each row carrying the company, roundType, amountUsd, announceDate and isLead fields behind the tables above, for 5 credits a call. Plans start at Essential, $49 a month for 3,000 credits, which is 600 data calls, and a key without enough credits gets clearly marked sample data so you can build before you pay: the endpoints are at naut.so/docs/api and the plans at naut.so/pricing. Verified Telegram, email and LinkedIn for the people on these company pages unlock on any paid NAUT plan, so start a 7-day trial if you want the contact channels as well as the rounds.

Big Brain Holdings portfolio FAQ

Which crypto companies has Big Brain Holdings invested in?

NAUT records 74 companies backed by Big Brain Holdings as of 2 November 2026, across 82 rounds. The largest by disclosed total are Avalanche at $250.0M, Monad at $225.0M, tenprotocol at $25.5M across 3 rounds, then Nillion, Oasys and MegaETH at $20.0M each, and by count the list leans on infrastructure (11 companies), AI (9), DeFi (8) and gaming (8).

How many companies are in the Big Brain Holdings portfolio?

74 companies and 82 round records on NAUT, counted on 2 November 2026, with rounds announced between November 2021 and October 2026. The stored summary field on the fund row held an older count of 80 investments at that snapshot, and the fund publishes no portfolio count of its own, so treat 74 as NAUT's coverage of the fund rather than its full history.

How much does Big Brain Holdings invest in a round?

Across the 80 rounds in NAUT's set that disclosed a size, the average round was $12.3M and 43 of the 80 were under $6M, measured between November 2021 and October 2026. Those are the sizes of the whole round, not this fund's own cheque, which these sources do not disclose.

Which funds invest alongside Big Brain Holdings?

NAUT records 245 other firms in these 82 rounds, and 16 of them share 6 or more. Animoca Brands, Infinity Ventures Crypto, NGC Ventures and Shima Capital lead that list at 8 rounds each, followed by Cogitent Ventures, GSR and Mirana Ventures at 7.

Does Big Brain Holdings lead rounds?

NAUT's data shows no lead flag for this fund on any of these 82 rounds, and only 1 of the 82 rounds names any firm as lead at all, so the absence is a gap in the record rather than a fact about the fund. NAUT's own profile of the firm describes it as an early-stage investor across gaming, consumer infrastructure, Web3 tools and DeFi, which matches the sector mix in the tables above.

Where can I find the teams behind these 74 companies and how to reach them?

Each of the 74 companies above links to its NAUT page, which lists the people on the team with the channels NAUT holds for each of them, and GET https://api.naut.so/v1/projects/<slug> returns the same company with its team for 5 credits. Verified Telegram, email and LinkedIn unlock on any paid NAUT plan, so start a 7-day trial to open the channels on those pages.

Sources

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